The Department of Cell and Developmental Biology is sad to share that our colleague, Dr. John Gearhart, passed away Thursday, May 28, 2020 following a long illness. John was a stem cell research pioneer and best known for leading the Johns Hopkins University research team that first identified and isolated human pluripotent stem cells from primordial germ cells. In 2008, he was named the Director of Penn’s Institute for Regenerative Medicine (IRM). John’s myriad contributions and accomplishments and his dedication […]
“Senotherapy,” a treatment that uses small molecule drugs to target “senescent” cells, or those cells that no longer undergo cell division, blunts liver tumor progression in animal models according to new research from a team led by Celeste Simon, PhD. The study was published in Nature Cell Biology. Full press release here.
Zhu Q, Gao P, Tober J, Bennett L, Chen C, Uzun Y, Li Y, Howell ED, Mumau M, Yu W, He B, Speck NA, Tan K.Zhu Q, et al. Blood. 2020 May 11:blood.2020004801. doi: 10.1182/blood.2020004801. Online ahead of print.Blood. 2020. PMID: 32392346
Yang F, Lan Y, Pandey RR, Homolka D, Berger SL, Pillai RS, Bartolomei MS, Wang PJ.Yang F, et al. Genes Dev. 2020 May 7. doi: 10.1101/gad.335489.119. Online ahead of print.Genes Dev. 2020. PMID: 32381626
Ren W, Medeiros N, Warneford-Thomson R, Wulfridge P, Yan Q, Bian J, Sidoli S, Garcia BA, Skordalakes E, Joyce E, Bonasio R, Sarma K.Ren W, et al. Nat Commun. 2020 May 6;11(1):2219. doi: 10.1038/s41467-020-15902-9.Nat Commun. 2020. PMID: 32376827
Capelson M. Dev Cell. 2020 Feb 10;52(3):252-254. doi: 10.1016/j.devcel.2020.01.019.Dev Cell. 2020. PMID: 32049034
Walker LJ, Granato M.Walker LJ, et al. Dev Cell. 2020 May 4;53(3):257-258. doi: 10.1016/j.devcel.2020.04.014.Dev Cell. 2020. PMID: 32369739