Shelley L. Berger, Ph.D.

Penn researchers uncover epigenetic drivers for Alzheimer’s disease

Research led by by Raffaella Nativio, former research associate in the Berger Lab, Shelley Berger, Daniel S Och Professor and director of the Epigenetics Institute, and Nancy Bonini, professor of Biology, suggest that late-onset Alzheimer’s Disease is driven by epigenetic changes—how and when certain genes are turned on and off—in the brain. Results were published in Nature Genetics. The identification of this epigenetic process highlights potential drug treatment strategies for early-stage disease treatment. Please read the Penn Today article here.