Emergent dynamics of adult stem cell lineages from single nucleus and single cell RNA-Seq of Drosophila testes

Amelie A Raz, Gabriela S Vida, Sarah R Stern, Sharvani Mahadevaraju, Jaclyn M Fingerhut, Jennifer M Viveiros, Soumitra Pal, Jasmine R Grey, Mara R Grace, Cameron W Berry, Hongjie Li, Jasper Janssens, Wouter Saelens, Zhantao Shao, Chun Hu, Yukiko M Yamashita, Teresa Przytycka, Brian Oliver, Julie A Brill, Henry Krause, Erika L Matunis, Helen White-Cooper, Stephen DiNardo, Margaret T Fuller (2023) Emergent dynamics of adult stem cell lineages from single nucleus and single cell RNA-Seq of Drosophila testes eLife 12:e82201.

Please read the publication here.

Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness

Gu L, Zhu Y, Watari K, Lee M, Liu J, Perez S, Thai M, Mayfield JE, Zhang B, Cunha E Rocha K, Li F, Kim LC, Jones AC, Wierzbicki IH, Liu X, Newton AC, Kisseleva T, Lee JH, Ying W, Gonzalez DJ, Saltiel AR, Simon MC, Karin M. Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness. Cell Metab. 2023 Apr 12:S1550-4131(23)00126-2. doi: 10.1016/j.cmet.2023.03.021. PMID: 37084733.

Please read the publication here.

Nancy A. Speck, Ph.D.

Nancy A. Speck Appointed as The John W. Eckman Professorship of Medical Science II chair

Nancy A. Speck, PhD has been appointed the chair holder of the John W. Eckman Professorship of Medical Science II!

Established in 2021, this is the second professorship from an endowment founded in 1989 to honor Rhône-Poulenc Rorer’s retired CEO John W. Eckman. Mr. Eckman, an alumnus of the Wharton School Class of 1943, was a celebrated industrialist committed to the enrichment of Philadelphia’s scientific, cultural, and educational communities. Mr. Eckman was a leader in the pharmaceutical industry for over 35 years who believed strongly that “being a good citizen is good business.”

Nancy epitomizes the spirit and practice of good citizenship on every level. As a member of the National Academy of Sciences, a highly accomplished scientist, and widely recognized international leader in hematology, Nancy is most deserving of this honor. In her career of over 30 years, Nancy has made significant contributions to understanding the role of RUNX1 and CBFβ in normal blood cells. Known as a transformative leader, Nancy is also a dedicated mentor with a strong commitment to diversity and inclusion. Congratulations, Nancy!

Andrew Modzelewski, B.Sc, Ph.D.

Andrew Modzelewski Named Searle Scholar

Congratulations to Andrew Modzelewski, PhD for being named a Searle Scholar! The Searle Scholars Program makes grants to selected universities and research institutes to support the independent research of exceptional young faculty in the biomedical sciences and chemistry. Please read the announcement here.