The goal of the UPenn Epigenetics Program is to advance basic and applied research in chromatin biology and epigenetics, building on current interest both in mechanisms underlying epigenetic regulation, and in unraveling genome-wide chromatin patterns, commonly known as epigenomes.

While genetic approaches to altering cell and tissue function involve direct perturbation of the genome, epigenetic strategies involve the use of small molecules to modulate enzymes and chromatin binding proteins and thus provide a novel approach for developing therapies and diagnostics to improve human health.

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